EUROMEDICA 

Hanover

29-30  Mai 2006

Advanced methods of diagnosis,
treatment and prophylactics

European Academy of Natural Sciences, Hanover

European Scientific Society, Hanover

Russian Academy of Natural Sciences, Moscow


G. Roytberg
E. Budko
T. Ushakova
J. Dorosh
DIETARY ALTERNATIVES IN THE COMPLEX THERAPY OF METABOLIC SYNDROME
Russian State Medical University, Moscow, Russian Federation

Background: Abdominal-visceral fat mass decrease ranks high in the complex therapy of metabolic syndrome (MS). A loss of 10-15% of total body mass leads to a decrease in the fat tissue visceral component, sensitivity to insulin improves and hyperinsulinemia decreases. The study was undertaken to examine the impact of diets containing different ratios of carbohydrates and fats on body weight loss and changes in life quality in patients.

Methods: Diet therapy was prescribed to 87 male subjects with abdominal fatty tissue distribution and dyslipidemia aged from 39 to 46 years old through the Department of Family Medicine multi-profile clinic. Subjects were not previously diagnosed with ischemic heart disease or diabetes mellitus type 2 and didn’t take any hypolipidemic therapy, beta-blockers or diuretics. Mild arterial hypertension was observed in 49.4% of cases. The diet was chosen by taking into account the taste and dietary habits of patient.

Results: The results of diet therapy were assessed following four months. Weight decrease dynamics and life quality changes were compared across 3 dietary courses: 1. low-carbohydrates diet (fats - 100 g, carbohydrates - 40 g), N=37; 2. low-fat (fats - 60 g, carbohydrates - 160 g), N=23; and diet with limited fat quantity (fats - 80 g, carbohydrates

- 130 g), N=27. The effective reduction in body-mass index (BMI) was achieved by using all the diets in question. Keeping to a low-carbohydrate diet caused the greatest BMI decrease (more than 22%) in the presence of good tolerability. The patients keeping to a low-fat diet had the decrease of BMI also near 22% with reported that they had limitations in choosing and cooking dishes and constantly felt hungry, which affected their subjective assessment of their tolerability. A balanced diet is well tolerated by patients but BMI loss being less effective (less than 20%).

Conclusions: Our results showed equal weight decrease in all groups, however life quality improvement and greater adherence were noticed after low-carbohydrates diet.