EUROMEDICA  Hanover 29-30  Mai 2006	Advanced methods of diagnosis, treatment and prophylactics
	European Academy of Natural Sciences, Hanover European Scientific Society, Hanover Russian Academy of Natural Sciences, Moscow

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The problems of prophylaxis and health-improvement are very actual for the practical medicine (Gelfand B.R. at al., 2003; Manns M.P., 2003; Pogodina V.A., 2004). Prophylaxis is now on that stage of the development when changing the notion about methods of prevention and rehabilitation of a disease is necessary (Tsukanov V.V., 2004). The arsenal of the modern measures makes it possible only to stop a disease at the stage of acute attack. All these facts predetermine a necessity to study the possibilities of the medicinal plants. According to the data of the leading phyto therapeutics, continuous prophylaxis of the acute attacks of a disease is more effective than prescription of the basic antirelapse medicines (Pastushenkov L.V. at al., 1995; Drozd G.A., 1997; Sokolov S. Y., 2000; Korsun

V.F. et al., 2003, 2005). Sometimes using the medicines has to be stopped because of arrived side effects. So the search of new alternative methods of prophylaxis, treatment and rehabilitation of a disease is considered to be perspective. Among them the health-improving lymphotropic technologies based on the concept of «lymphatic region» (Borodin Y.I., 1998, 2004) and nutritiology (Gorchakov V.N., 2000, 2004) attract attention.

At the present article the efficacy of the lymphotropic technologies is estimated on the base of dynamics of microelement compounds of the structures forming so named «lymphatic region» at the condition of dysfunction of the thyroid gland and its correction with original phytoadditives. Hypothyroidism model with per oral taking the day dose 3 mg/kg of mercazolilum was used. The roentgen-fluorescent analysis with synchrotron radiation (SR XRF) was used for the estimation of microelements at the biologic objects of «lymphatic region» (blood, lymphatic node, and organ). The SR XRF was carried out at the station of element analysis of SR Centre on VEPP-3 at Budker Institute of Nuclear Physics of SB RAS (Novosibirsk).

The disorder of the biological constants of organism is connected with the transition from health to disease and the restore of this disorder is the main aim of medicine (Baevsky R.M., 2000; Gutebrunner S., 2003; Gerke A., 2004). The microelements play the important role among the many constants because they possess polyfunctional qualities. The one of the significant element is selenium which ensures the antioxidant protection at the physiologic and pathologic conditions. This ability makes it alike with thyroid hormones. The character of interconnection between the content of selenium in the different structures of «lymphatic region» of thyroid gland confirms the existence of specific structural functional unit namely «lymphothyreostate». At the hypothyroidism selenium accumulates in the lymphatic node (+35%), the thyroid gland (+41%) and decreases slightly in the blood (-6%). Selenium comes from blood channel into interstice and then into thyroid gland and lymphatic node. After abolition of mercazolilum at the stage of rehabilitation without taking the phytoadditives selenium accumulates in the lymphatic node (+47%), decreases in the thyroid gland (-32%) and increases slightly in the blood (+4).The concentration of selenium in the thyroid gland during the period of rehabilitation without exogenous source of selenium is considered to deplete. Moreover using the original phytoadditives at the stage of rehabilitation leads to the increase of selenium in the lymphatic node (+104%), in the blood (+28%) and to the normalization it in the thyroid gland (-10%). At the stage of rehabilitation the distribution of selenium comes from interstice and thyroid gland into blood channel and lymphatic node. The intensity of this process enforces by receiving the exogenous selenium from phytoadditives. Exactly the lymphatic node in the «lymphothyreostate» accumulates selenium at the different structural and functional states of the thyroid gland. Redistribution of selenium between the structures is connected with the increase of antioxidant status, the optimization of sanitation effect of the lymphotropic technologies and the restoration of the euthyroid state of organism.

The obtained data are the base for developing the phytolymphonutritiology and for using the lymphotrophic technologies in prophylactic and rehabilitation medicine