EUROMEDICA  Hanover 29-30  Mai 2006	Advanced methods of diagnosis, treatment and prophylactics
	European Academy of Natural Sciences, Hanover European Scientific Society, Hanover Russian Academy of Natural Sciences, Moscow

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Lymphatic system is one of the key links in the homeostasis and humoral transmission system. Lymphodrainage disturbance influences on the development and outcome of most diseases. Optimization of lymphatic system inadequate functions is the important principle of clinical lymphology and its methods are successfully used in modern medicine.

Aim: analysis of lymphotropic therapy and endoecological rehabilitation efficiency for the treatment of urinary excretion organs microbial inflammatory diseases of children.

Methods: 36 children with microbial inflammatory diseases of urinary excretion organs at the age from 3 to 9 years were under the observation, mean age 5,4 ± 0,6 years. By the results of ultrasonic examination of children abdominal cavity organs we can exclude urogenital system abnormalities. Bacteriological investigation of urine detected in diagnostic titers 75% cases of Escherichia coli and 25% cases – Proteus spp. During the laboratory examination moderate leukocytosis and increasing of ESR (erythrocyte sedimentation rate) were observed in 41,7% of the children, transitory proteinuria – in 25%, an increased content of leukocytes – 100%, increased content of erythrocytes – 16,7%. 1 group (9 people) was treated with a standard regimen (3 courses of antibacterial therapy inside or by parenteral dosing, spasmolytics, disaggregants, and antioxidants). With the purpose of restoration of disturbed tissues lymphodrainage, increasing of local immunity and sanation of nidus of infection in the urinary excretion system in 2-nd group (27 people) for all patients were carried out two courses (10-14 days) of endoecological rehabilitation by Levin (ERL): Сatreli in combination with systemic enzymotherapy (Wobenzymi), cholagogic, sorbent, polyvitaminic mineral complex. Selected by the sensitivity antibiotic was introduced once a day during 10 days by lymphotropic into inguinal paranodular region by the technique by L.M. Yurjin in the dose equal to half-single dose, because lymphotropic method of introduction enables to form high concentration of antibiotic in the pathologic center during the day. Electrophoresis with Terrilytini was carried out by general and regional technique. A course of Polyoxidonii injections was conducted for the children of both groups after completion of the antibiotic therapy.

Results: in all children groups urine sanation (general microbe number GMN<10³ KOE/ml) was attained. In the group, which received a lymphotropic therapy, normalization of bulk urine test was observed on average 3-4 days earlier, there were no recurrences of microbial inflammatory diseases of urinary excretion organs. None of children had some complications or side effects.

Conclusion: opportunity of successful application of lymphotropic therapy and endoecological rehabilitation for the treatment of urinary excretion organs microbial inflammatory diseases of children was shown. Lymphotropic method of antibiotic introduction in contrast to traditional method doesn’t bring to forming of regional lymph nodes sclerosis and to dropping of resistance of urogenital tract mucous tunic, and prevent from develop of recurrences. Thus, lymphotropic method of antibiotic introduction in combination with endoecological rehabilitation can be used as effective, alternative for the conventional method of treatment of microbial inflammatory diseases of urinary excretion organs in children.