EUROMEDICA 

Hanover

1-2  Juni 2007

Advanced methods of diagnosis,
treatment and prophylactics

European Academy of Natural Sciences, Hanover

European Scientific Society, Hanover

Russian Academy of Natural Sciences, Moscow


N.E. Gelfond
A.S. Chukanov
O.V. Shuvaeva
INVESTIGATION OF MINERAL STRUCTURE OF THE CENTRAL LYMPH AND PERIPHERAL BLOOD IN CONDITIONS OF ADIPOSITY AND PHYTOCORRECTION
State research institute of clinical and experimental lymphology SB RAMS, Novosibirsk, Russia
“Laboratory of lymphotropic technologies”, “Scientific research firm Harmony VITA”, Novosibirsk, Russia

Adiposity is a serious medical, social and economic problem in the modern society. The universal tendency to decrease in people with insufficient weight is almost equivalent to the quantity of people with excess weight and adiposity. About 7 % of the population of the globe suffers from adiposity. The feed structure leads to infringements of the food status in the developed countries inevitably on the background of superfluous consumption of animal fats and deficiency of mineral substances. Dysbalance of macro-and microelements is one of the consequences of many pathological conditions caused by adiposity. Correction of the macro-microelement status of an organism is possible due to use of the functional foods containing essential nutrients.

The purpose of the work was to estimate changes of the mineral structure and efficiency of the functional food “Lymphovit P” and phyto-tea “Herbanorm” in conditions of alimentary adiposity; to prove feasibility of application of these functional foods for dietological correction of alimentary adiposity by means of improvement of functional condition of the liver, gallbladder, gastrointestinal tract. Investigation was conducted on the basis of quantitative estimation of changes in macro- and microelement structure of the peripheral blood serum and central lymph.

Methods. Analytical investigations were carried out by the methods of atomic fluorescence spectrometry. The chemical compound of the blood serum and lymph was defined on 12 elements (Al, Ba, In, Ca, Cu, Fe, Mg, Mn, P, Pb, Sn, Zn) for following groups of animals (male rats Wistar): 1) animals with standard vivarium ration; 2) animals with lard in ration (2 - 2,5 г on one animal); 3) animals with lard in ration and dietological correction by phytosorbtional complex “Lymphovit P”; 4) animals with lard in ration and dietological correction by phyto-tea “Herbanorm”.

Results and discussion: The obtained results testify that micronutrient balance between the lymph and blood is seriously impaired in the animals with alimentary adiposity. High concentrations of animal fats in the diet have led to sharp (practically twofold) decrease in the maintenance of calcium and phosphorus in the blood serum as compared to the control group. In our opinion decrease in calcium concentration has influenced an increase of lead and iron maintenance in the blood serum, as, from one point, calcium promotes deduction of salts of heavy metals from an organism, and, from the other point, calcium is an antagonist of iron. Normalization of the element status is observed in condition of phyto-dietological correction by functional food “Lymphovit P”, concentrations of lead and low down, the maintenance of phosphorus comes closer to the norm, the maintenance of calcium increases by 20 %, the tendency to normalization of microelement balance between the lymph and blood is revealed. Normalization of mineral structure in the system blood-lymph does not occur with administration of phyto-tea “Herbanorm” as the phyto-tea is not a source of mineral substances. Marked decrease in the maintenance of lead and iron in blood serum down to norm is connected apparently with formation of difficultly acquired salts of iron with tea theine, catehine and caffeine, containing in green tea in the structure of phyto-tea “Herbanorm”. Use of phyto-tea leads as a whole to improvement of motility of the digestive tract, and as a consequence to decrease in central lymphflow closer to the norm (in 5 - 6 times as compared with alimentary adiposity) due to specially selected vegetative components with gastroprotective effects.

Conclusions: Use of phytocomplex “Lymphovit P” as dietological correction promotes restoration of the macro-microelement balance impaired due to malnutrition. Application of “Lymphovit P” and phytotea “Herbanorm” under condition of alimentary adiposity enables to improve the digestive function, reduce absorption of alimentary fats and as a consequence, to decrease lipid loading without increase in calorie intake.