EUROMEDICA  Hanover 1-2  Juni 2007	Advanced methods of diagnosis, treatment and prophylactics
	European Academy of Natural Sciences, Hanover European Scientific Society, Hanover Russian Academy of Natural Sciences, Moscow

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Actuality of the problem: nephrolithiasis (kidney stones) – a pathology that spreads endemically. This is facilitated by a number of factors. External factors – individual diet (excessive consumption of products containing too much calcium and too little retinol, too much mineralized water, staying in hot dry climate, lack of movement over a long period of time). Internal factors – hereditary susceptibility to accumulation of salts (diathesis). Among risk factors are inborn and acquired modifications in urinary tracts as well as intake of some drugs. A certain role in development of nephrolithiasis is played by the endocrine system, particularly disturbances in the functions of parathyroid glands. Their hyperfunction causes hypercalcemy and hypercalcuria which might account for formation of stones in pelvises.

The mechanism of development of urinary concretions: molecules of calcium crystals are joined into polymorphous units and due to lack of protective colloids are grouped and form micelle, which results into formation of concretions. Stone formation depends on salt concentration in urine, chemical structure of urine colloids and the urine рН. Acid reaction is of a urate origin, base – of phosphate origin.

Materials and methods of the investigation: We selected for examination and treatment 109 patients (74 men and 35 women) aged: 2 patients younger than 20 years; 8 patients - 21-30 years; 11 patients of 31-40 years; 15 patients of 41-50 years; 47 patients of 51-60 years; 23 patients of 61-70 years; and 3 patients of 71-80 years.

In 16 patients by ultrasound screening were detected concretions in pelvises of the size 1-2 mm, in the rest patients the concretions were bigger. Uraturia was observed in 61% cases, oxalaturia - in 23% cases, combination of oxalat- and phosphaturia – 11% cases and the combination of carbonat – and phospaturia – in 5%.

Essential oil of Citrus Limon (L) was administered for treatment produced by Swiss company «Elixan Aromatika».

Depending on the diameter of concretion oil intake was conducted under different schemes: a 21-day course for 1-2 mm-concretion – 1 drop with sugar or honey 1 time a day and for concretion of 3-5 mm –1 drop 2 times a day also a 21-day-course with an interval of 7 day followed by 2 additional 21-day courses. If the stone was bigger than 5 mm one drop was given twice a day within 2-3 months without an interval.

Results: After the treatment the following data was obtained: the stones of the urate origin were completely diluted in 78% cases; in 22% cases they were scientifically reduced. Oxalate concretion were hardly diluted, they were mostly fragmented.

Conclusions: Thus our investigation proved that Essential oil of Citrus Limon (L) produced by Swiss company «Elixan Aromatika» can be used for treatment of nephrolitiasis of the urate origin and dysmetabolic nephropathies of diverse etiologies.