| T.V. Kobets |
INTRODUCTION OF MODERN MEDICAL TECHNOLOGIES AT THE
STAGE OF SANATORIUM- AND- HEALTH RESORT TREATMENT OF CHILDREN WITH RECURRENT
BRONCHITIS (RB) |
| Crimean State Medical University, Simferopol, Ukraine
|
Evpatoria is a children health centre where children with diseases of respiratory
apparatus undergo rehabilitation. However during the last years the course of
treatment at a resort has reduced sharply to 24 days. In accordance with this
fact medical load on the patients has increased. It has resulted in the situation
that children with reduced adaptation, first of all due to ecologically
unfavorable regions are frequently sick with RB at sanatorium and are not able
to undergo a complete course of treatment. Earlier we have shown that in children
with RB at the resort parameters of cellular immunity were reduced in comparison
with healthy children, and these changes are more expressed in children from
ecologically unfavorable regions. To increase adaptation it is possible to use
a dietary additive Polysim-4 elaborated by the Crimean scientists. The purpose
of research was to study the influence of Polysim- 4 on adaptation of
children with recurrent bronchitis from ecologically unfavorable regions at
a resort. Methods. For solution of set problem we have examined 19 healthy children
and 83 children with RB from ecologically unfavorable regions. On admission
and discharge from sanatorium all children were subjected to clinical, immunological
(+ CD 3, +CD 4, +CD 8; Ig A, IgM, IgG, subclasses JgG: Ig G1, IgG2, IgG3, IgG4;
NBT-test) methods of investigation. The 1
st group was made of 41
patients, which received: dietotherapy, sparing regime with obligatory sleep
during daylight hours, bathing in the sea, mud applications, low-frequency physiotherapy,
aerotherapy, laser irradiation and circular douche, sodium chloride baths (10
procedures), manual massage of the chest. In the 2
nd group there
were 42 children with RB which got extra food additive Polyzim-4 (1 tea spoon
2 times a day during 24 days). Polyzim-4 is complex polyenzymatic formula containing
enzymes, cytomedines, polyunsaturated fatty acids, phospholipids, amino acids,
essential oils, bioflavonoids, vitamins (C, B1, B2, B12, D, K, PP, H (biotin),
beta-carotin), microelements (Fe,Ca, K,Na, P, Mg, Cu, S, Zn). Results. As the
research has shown in all investigated children + CD 3, +CD 4, +CD 8 were authentically
reduced on admission. On discharge + CD 3, +CD 4, +CD 8 increased in both groups,
however they reached control values in the 2
nd group only. On admission
IgG level was reduced in both compared groups and on discharge it increased
reaching control values. In group of children who got Polysim-4 IgM on admission
was higher than in the control and that was apparently connected with the presence
of chronic foci of infection in 6 children. On discharge IgM became normal and
IgM level in the 1
st group children increased, that was clinically
accompanied with development of RB in 4 children. IgA was increased in both
groups on admission and became normal on discharge. NBT-test on admission was
higher in the 2
nd group of children (in 6 children foci of chronic
infection took place) and became normal on discharge.While NBT-test in the 1
st
group increased on discharge (that was the evidence of antigenic load),
combined with the increase of IgM in blood serum and manifested itself clinically
by development of RB in 4 children, IgG
1 and IgG
4 level
in blood serum was reduced on admission and discharge in all children. IgG
2
on admission was above the line in both groups and became normal only in the
1
st group children. IgG
3 on admission was high in the
2
nd group and didn’t distinguish from the norm on discharge
in both groups. It is extremely important because subclasses IgG
1
and IgG
3 are powerful opsonins of activation of complement by alternative
way. It is necessary to note that none of the 2
nd group children
fall ill with RB at the resort. Conclusion. Polysim-4 contributes to the increase
adaptative-compensatory opportunities of children with RB by means of increase
of cellular immunity, stimulation of nonspecific resistance that allowed
to us to recommend Polysim-4 to children with RB from ecologically unfavorable
regions at the resort.
