EUROMEDICA  Hanover 6-7  Juni 2008	Advanced methods of diagnosis, treatment and prophylactics
	European Academy of Natural Sciences, Hanover European Scientific Society, Hanover Russian Academy of Natural Sciences, Moscow

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All metabolic matters using in the cells vital functions, are bounded noncovalent up with molecules of water almost constantly, that is why those moving from the blood flow to the interstitial space and then into the cells is due to the convection, it means with the water molecules. The water’s sense of current depends on two forces: the gradient pressure between osmotic and hydraulic pressure. For example, transmural osmotic blood pressure is near 25 mm.hg., thus if transmural hydraulic pressure in the change vessels rises above 25 mm.hg. the liquid moves out, if it declines - molecules of water move back into the vessels.

It was thought for a long time that the fluid goes out from arterial vessels and is absorbed in the veins capillaries. We were shown in our work, the liquid flows from one bloodstream to the other due to the pressure gradient. The illustrative example of that are eyeballs vessels. The liquid goes out from the ciliary body and choroid and is taking up by the retinal vessels. The unbalance between these vessels systems can cause severe retinal diseases.

The hemorrhagic retinopathy is the result of acute rising of transmural blood pressure (osmotic or hydraulic) in retinal change vessels. Hydrostatic higher pressure can be appear in the arterial hypertension, the retinal veins thrombosis, during Valslve’s test and others conditions, what accompanied by retinal edema. If osmotic transmural pressure was high (diabetes, acute and chronic renal impairment, paraproteinemia and etc.) liquid moves out of the retinal tissue, what cause rising of hydraulic transmural pressure in this change vessels, which lead to extravasations and hemorrhages. In such variant microaneurysms are mostly observed. The combination both of these factors is possible.