EUROMEDICA  Hanover 3-4  Juni 2010	Advanced methods of diagnosis, treatment and prophylactics
	European Academy of Natural Sciences, Hanover European Scientific Society, Hanover Berliner Medizinischen Gesellschaft, Berlin

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Introduction. Surgical intervention in case of pancreatic cancer is still the basic method of its treatment. Nevertheless, 5-years survival rate is still low, it makes from 5 up to 12%. One of the reasons of these unsatisfactory results is difficulties in adhering to ablastics principles at mobilization of pancreas from surrounding tissues.

Purpose. Using pancreatic cancer cryotherapy with deep freezing of surrounding tissues - to create optimum conditions for prevention of translocation of tumoral cells to blood and lymph flow during radical operations.

Materials and methods. There were 28 patients under the observation, the patients have undergone pancreatic cancer surgery with liquid nitrogen cryotherapy. In 14 cases it was pancreaticoduodenal resection, in 12 cases – distal resection, in 2 cases - pancreatectomy. Cryotherapy was performed repeatedly during the operation with the final stage at the bed of the removed part of the pancreas. For this purpose we have been using domestic device “Cryo-MT”, the applicator temperatures was -180°С.

Results and consideration. During the period of cryotherapy at the tumor zone, it was always possible to get “ice block” of tumor and surrounding tissues. In such cases the exposure of the affected part of pancreas was accompanied with minimum traumatization and low amount of blood and plasma loss. Mobilization from the main vessels was convenient and technically simple. Three-year observation has enabled to count on an improvement of the results of surgical treatment of pancreatic cancer patients. So, of 28 operated patients, 15 have died (53,6 %).

Conclusion. Application of cryotherapy at radical surgical interventions concerning pancreatic cancer helps to improve considerably a three-year survival rate, which is attributed first of all to the increase in ablastics during surgical intervention.