EUROMEDICA  Hanover 3-4  Juni 2010	Advanced methods of diagnosis, treatment and prophylactics
	European Academy of Natural Sciences, Hanover European Scientific Society, Hanover Berliner Medizinischen Gesellschaft, Berlin

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In this study we researched by histological method cellular structure of diffuse lymphoid tissue and fallopian tube lymphoid nodules of newborn girls in condition of contralateral aplasia of fallopian tube and compared the indices with those of the newborn girls with normal topographic anatomic shape of the organ. Comparing percentage of different types of lymphoid cells we found out that in condition of contralateral aplasia in comparison to control group there were 2 times fewer large lymphocytes (p<0,05), while middle lymphocytes, on the contrary, 2 times more (p<0,05), macrophages and mast cells – 1,4 times more (p<0,05), cells with signs of destruction – 4,6 times more (p<0,05). In condition of contralateral aplasia of fallopian tube in diffuse lymphoid tissue there were no cells with mitosis picture (in control group they make up 1%).

In fallopian tube lymphoid nodules of newborn girls in condition of contralateral aplasia of fallopian tube there are 1,92 times more small lymphocytes (p<0,05) than in control group, 2 times more large lymphocytes (p<0,05), 1,56 times more middle lymphocytes (p<0,05), 1,7 times more macrophages (p<0,05), while blasts and cells with signs of mitosis are 2 times fewer (p<0,05) in comparison to control group. In condition of contralateral aplasia in fallopian tube lymphoid nodules there were 4 times more cells with signs of degeneration (p<0,05) than in control group, 1,8 times more mast cells (p<0,05), 2,5 times more eosinophils (p<0,05). The 2 latter cell types were not found in fallopian tube lymphoid nodules of control group girls.

Minimal and maximal percentage of different types of lymphoid cells in fallopian tube lymphoid nodules in condition of contralateral aplasia of fallopian tube is as different in comparison to control group as in case of arithmetical mean indices.

We found out as well that newborn girls with contralateral aplasia of fallopian tube have fallopian tube wall in general 1,95 times thinner than normally it should be, p<0,05, mucous membrane 2,58 times thinner (p<0,05), muscle coat – 1,9 times thinner (p<0,05) which altogether is the evidence of the contralateral organ congenital underdevelopment. Parallelly, lymphoid nodule gets 1,46 times shorter and nodule area on the fallopian tube section 1,75 times smaller. Lymphoid nodule shape changes and in 24% cases becomes irregular. In control group, on the contrary, there are no irregularly shaped nodules at this age. According to M.R. Sapiga and D.B. Nikityuk (2000), lymphoid formation shape becoming irregular indicates that lymphoid tissue gets disintegrated.

Thus, we can conclude that fallopian tube lymphoid apparatus of newborn girls suffering from contralateral aplasia of fallopian tube is morphologically regressive: lymphoid nodules get thinner and smaller on fallopian tube section, quantity of lymphoid cells in lymphoid nodules and diffuse lymphoid tissue decreases, as well as quantity of small lymphocytes, young lymphoid cells, plasma cells; fallopian tube wall gets thinner in general and its mucous membrane and muscle coat in particular.