EUROMEDICA  Hanover 23-24  Mai 2011	Advanced methods of diagnosis, treatment and prophylactics
	European Academy of Natural Sciences, Hanover European Scientific Society, Hanover

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Course of pregnancy, birth and prenatal outcomes were studied among 200 women at term pregnancy. The main group contained 100 patients, identified at a risk group, who were taking medicines for the prevention of intrauterine growth retardation according to our especially developed method. The comparison group included 100 pregnant women, identified at risk, who refused the suggested method. The women of the main and comparison groups were comparable by all rates with minor differences. We developed a method of medicamental prenatal prevention of fetus’ intrauterine development retardation for the risk group women, which was an additional medication for 10-14 days in the period of 14-16, 20-24, 30-34 weeks of pregnancy. According to the method the main group was prescribed natural micronized progesterone (200mg) 0.007oz. intravaginally 2 times daily up to 18 weeks – gestagenic drug with a selective effect on the endometrium, a complex of essential polyunsaturated fatty acids of omega-3 family – as an antioxidant, combined multivitamin complex with micro and macro elements, potassium iodide (200mg) 0.007oz. per day. The complex included dry aqueous extract of fresh Artichoke leaves, 2 tablets 3 times a day – hepatoprotector of plant origin. To improve the metabolism of protein and fat Levocarnitine was used, 8 drops 3 times a day – a natural substance akin to B vitamins.

At 14-16 weeks a preventive treatment in day hospital was prescribed with additional inclusion of deproteinized gemoderivat made of calf blood with low molecular weight peptides and nucleic acids derivatives and nadroparin calcium 0.3 n/a, by indication, into the complex.

In the comparison group vitamin therapy and iodine medicines were recommended at first attednance. The pregnant women refused proposed preventive treatment of FGR and placental insufficiency.

At ultrasound at 32-34 weeks of gestation period 88% of women of the main group were detected with the ^st degree of the placenta’s maturity, estimated fetal weight was 2470g ± 120g. 8 pregnant women (8%) were detected with the 1^st degree of intrauterine growth retardation and asymmetric shape. Blood flow disorders and CTG changes were not found.53% of the women of the comparison group at 32-34 weeks of pregnancy had 2-3 degrees of the placenta’s maturity, estimated fetal weight was 2120g ± 142g. 19 pregnant women (19%) were detected with the 1 degree of FGR and asymmetric shape. The pregnancy of the main group women completed with spontaneous birth in 97.0% of cases, the comparison group women – 79.0%. 3 women of the main group were operated on the combined indications, and 21 of the comparison group according to the data of the fetus. The birth weight of a child of the main group women exceeded 3.100g in 92% of cases, all the children were born without signs of fetal development retardation. In the comparison group 31% of children were born with the signs of intrauterine growth retardation and the birth weight was less than 3.000g. The detection of pregnant women with the risk of birth of term children with the fetal growth retardation syndrome and the development and implementation of preventive measures is a way of the improvement of children’s individual health.